INJECTABLE TREATMENTS

Polynucleotides

Polynucleotides are advanced regenerative injectable treatments designed to repair, strengthen and rejuvenate the skin at a cellular level. At Beauttitude Medical Clinic in Sale, Greater Manchester, polynucleotide treatments are performed as part of personalised doctor-led skin regeneration programmes focused on improving skin quality, collagen production and long-term skin health.

What Are Polynucleotides?

Polynucleotides are highly purified DNA-derived molecules used in regenerative aesthetic medicine to stimulate tissue repair and cellular regeneration.

Rather than filling or volumising the skin, polynucleotides work biologically by improving how skin functions and heals.

They act by:

✔ Stimulating fibroblast activity
✔ Increasing collagen production
✔ Improving skin elasticity
✔ Supporting tissue repair
✔ Reducing inflammation
✔ Improving skin hydration indirectly

This makes polynucleotides a true regenerative treatment, supporting skin restoration rather than cosmetic masking.

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Treatment Summary​

1 hour

Discomfort is minimal and do require a topical anaesthetic prior to the procedure.

Noticeable improvements in skin texture and hydration  are noticeable after 3 treatments at intervals of 2-4 weeks.

Enjoy the benefits for up to 6 months The number of sessions needed will depend on skin condition and will be discussed during consultation.

From £275

How Do Polynucleotides Work?

After injection, polynucleotides interact with skin cells to activate regenerative pathways.

They help to:

• stimulate collagen and elastin synthesis
• improve microcirculation
• support cellular repair mechanisms
• neutralise oxidative stress
• strengthen the extracellular matrix

This biological stimulation improves skin structure gradually, resulting in healthier, stronger and more resilient skin.

Results develop progressively as the skin regenerates naturally.

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How is the treatment administered?

olynucleotide treatment at Beauttitude Medical Clinic is performed following a detailed medical consultation and skin assessment.

Step 1 — Medical Consultation & Skin Analysis

Your skin condition, medical history and treatment goals are assessed to determine suitability.

Step 2 — Skin Preparation

The treatment area is cleansed and numbing cream may be applied to improve comfort.

Step 3 — Precise Micro-Injection Technique

Small amounts of polynucleotides are carefully injected into targeted skin layers using advanced medical techniques designed for even distribution and optimal regeneration.

Step 4 — Post-Treatment Care

Soothing skincare and personalised aftercare advice are provided to support healing and results.

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What Skin Concerns Can Polynucleotides Treat?

  • Polynucleotide treatments are particularly effective for:
    • Under-eye dark circles and crepey skin
    • Skin laxity and thinning skin
    • Fine lines and early ageing
    • Acne scarring
    • Rosacea-prone or sensitive skin
    • Dehydrated or damaged skin
    • Loss of skin elasticity
    • Preventative anti-ageing treatment
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How It Works

Frequently Asked Questions

Downtime is minimal.

You may experience:

  • mild swelling

  • redness

  • small injection marks

  • occasional bruising

These usually settle within a few days.

Most patients benefit from an initial course of 3–4 treatments spaced several weeks apart.

Maintenance sessions may be recommended depending on skin condition and treatment goals.

Your treatment plan is personalised following consultation.

Polynucleotides are suitable for patients who wish to improve skin quality and support natural regeneration.

They are particularly beneficial for:

  • patients noticing early skin ageing

  • patients with delicate or thinning skin

  • patients seeking subtle rejuvenation

  • patients wishing to support skin health alongside other aesthetic treatments

Suitability is always assessed during your consultation.

Yes.

Polynucleotides are often combined with:

  • skin boosters

  • microneedling

  • laser skin treatments

  • anti-wrinkle injections

  • Zaffiro skin tightening

This combination approach supports overall skin health and long-term rejuvenation.

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my mission

My Goal is to Provide the Highest and Safest Quality Service

My story continues with every patient I meet, every skin journey I guide, and every moment I choose intention over impulse

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SKIN CONCERNS

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Under Eye Rejuvenation

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Skin Agening and Laxity

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SKIN CONCERNS

Rosacea and Redness

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Pigmentation and Melasma

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SKIN CONCERNS

Acne

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Success Stories

More than 250 five-star reviews on Google and Fresha

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Annera Hanif profile picture
Annera Hanif
14:23 03 Feb 26
I first visited Dr Gabs for acne scarring and have already seen such a noticeable difference after just one treatment! She really took the time to listen to my concerns and advise with such knowledge and detail, and I cannot wait to continue the journey with her moving forward.
Luiza Stihi profile picture
Luiza Stihi
13:24 03 Feb 26
Dr. Gabs is very professional and genuinely kind. She made me feel comfortable from the start and explained everything clearly. You can tell she truly cares about her patients. I’m really happy with my experience. Would definitely recommend 😊
corinna Jayne profile picture
corinna Jayne
13:18 03 Feb 26
Talented and knowledgeable! Amazing service 🤩
Emma Cooper profile picture
Emma Cooper
22:57 18 Dec 25
Dr Gabs is a really lovely lady, an absolute true professional - very knowledgeable and explains everything in great detail, have been using the products for a month now , that Gabs recommended for my skin type , I can see a noticeable change in my skin , and have had compliments on how “fresh “ I look !
Would highly recommend using Dr Gabs. ⭐️⭐️⭐️⭐️⭐️
Vicki profile picture
Vicki
07:44 31 Oct 25
Alan Apolakiatis profile picture
Alan Apolakiatis
17:43 30 Oct 25
What can I say?! Gabs is amazing at what she does! My skin felt amazing after my laserme and hydro deluxe treatment! She takes so much time explaining everything and provides fantastic aftercare!

Thanks again and see you soon!
Vlad Mircea profile picture
Vlad Mircea
17:19 30 Oct 25
The procedure I tried combined deep skin rejuvenation with hydration and glow enhancement, using targeted micro-injections and professional skincare formulas. The treatment felt comfortable — no pain, minimal redness, and zero downtime. My skin immediately looked smoother, firmer, and more luminous, with a visible reduction in dullness and fine lines. Over the next few days, the glow only got better.

It’s ideal for anyone who wants instant radiance and long-lasting hydration without invasive procedures. Definitely worth it if you’re looking to refresh tired or uneven skin quickly and safely!
Elena Voroneanu profile picture
Elena Voroneanu
14:55 30 Oct 25
I had lip filler treatment and Botox treatment with Dr Gabs. I cant be more happy with the result …so natural and painless !! Im over the moon with my lips and botox result . Dr Gabs is so lovely and friendly which make me feel so comfortable and I trust her with everything she recommends. Thank you and i cant wait for next treatment .
Jody Findley profile picture
Jody Findley
08:51 18 Oct 25
I went to see Dr. Gabriela as I was turning 40 and wanted to try Botox and a skin treatment for the first time. From the moment I met her, Dr. Gabs was absolutely amazing — warm, professional, and incredibly supportive. She took the time to explain every single step of the process, answered all my questions with care, and made sure I felt comfortable and confident throughout.

Her attention to detail and gentle approach made the whole experience so reassuring. My skin has never looked better — fresh, natural, and glowing — and I’m so happy with my results. I honestly couldn’t have asked for a better first experience. Highly recommend Dr. Gabriela to anyone thinking about starting their skin journey!
Mark Davies profile picture
Mark Davies
11:35 22 Sep 23
First time I’ve had any form of treatment, Dr Gabriela was extremely professional and informative, put me at ease and before I knew it the treatment had been completed. Excellent experience.
Emma Green profile picture
Emma Green
16:46 04 Sep 23
I have been visiting Dr Gabs for over 6 months and the results are amazing. She is a fountain of knowledge and an outstanding aesthetic Doctor. Highly recommended.
Leanne Gregory profile picture
Leanne Gregory
13:58 17 Jul 23
It was my first time visiting Dr Gabriella a few weeks back, she was recommended by a friend. She was very professional and explained everything clearly, giving recommendations but not in a pushy way. A very friendly and kind person, who put me at ease as soon as I arrived. I had Botox on my frown and eye area and a month on I’m loving the results - very subtle but exactly what I wanted. I will definitely be a regular customer from now on and I would definitely recommend. Thank you so much Dr Gabriella - you’re amazing!
Anastasia Lynn profile picture
Anastasia Lynn
21:43 13 May 23
Dr Gabriella is absolutely brilliant! I have had treatment from her for many years and have followed her as she changed clinics because she is so good at her job. Having previously tried out other well known clinics I have found her to be far superior. She is extremely experienced, professional and knowledgeable. She is honest in her advice to her clients, and never seems pushy. I could not recommend her enough.
Karolina Fedak profile picture
Karolina Fedak
08:20 10 May 23
Dr. Gabriella is a nice and friendly person, and she is very professional, she explained everything very well what the procedure is and how to perform it, I am very happy with the treatment.
I highly recommend ⭐️⭐️⭐️⭐️⭐️
J H profile picture
J H
01:16 08 May 23
Love the professional style of Dr Gabs. She will ask the right questions and offer advice on treatments and products to use in a non pushy style. You can see her expertise and experience in the way she injects. This was one of the reasons I left my last cosmetic nurse and I won’t be leaving Dr Gabs, been very happy with the results of my Botox treatment and considering further treatments from her.
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